AVX 13616

CAT: 0931-T14359Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T14359Size:25 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
900814-48-4
Target
Others|||Antibacterial
Related Pathways
Microbiology/Virology|||Others
Bioactivity
AVX 13616, Avexa's leading antibacterial candidate, demonstrates significant in vivo antibacterial efficacy, especially against drug-resistant Staphylococcus pathogens, with an IC50 value of 2-4 µg/ml (MICs) and is targeted as an antibacterial agent. Comparable in activity to mupirocin within a nasal decolonization model, AVX13616 necessitated only a single application for effectiveness. This compound, alongside others, exhibited broad-spectrum antibacterial action, achieving MICs of 2-4 micrograms per milliliter against various isolates, including S. aureus, coagulase-negative staphylococci, enterococci, MRSA, VISA, and VRSA. Aimed for topical use and the treatment of wound infection or catheter-related infections, a solitary 5% (w/w) AVX13616 application (roughly equivalent to 2% mupirocin) proved as efficacious as twice-daily 2% mupirocin over five days in decolonizing MRSA in mice.
Smiles
O=C(C(CC(C)C)NC(C(CCCNC(N)=N)NC(C(CCCCN)NC(COC1=C(C2=C(C=CC3=C2C=CC=C3)OCCC(C)C)C4=C(C=CC=C4)C=C1)=O)=O)=O)OCCC(C)C.Cl.Cl
Molecular Formula
C50H73Cl2N7O7
Molecular Weight
955.08
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products