Praziquantel

• CAS Number :

  55268-74-1

• Target :

  Parasite|||Calcium Channel|||Antibiotic

• Related Pathways :

  Membrane transporter/Ion channel|||Metabolism|||Microbiology/Virology

• Purity :

  0.9986

• Bioactivity :

  Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

• Smiles :

  O=C(C1CCCCC1)N1CC2N(CCC3=C2C=CC=C3)C(=O)C1

• Molecular Formula :

  C19H24N2O2

• Molecular Weight :

  312.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C