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Praziquantel

CAT: 0931-T1435-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T1435-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55268-74-1
Target
Parasite, Calcium Channel, Antibiotic
Related Pathways
Membrane transporter/Ion channel, Metabolism, Microbiology/Virology
Purity
0.9986
Bioactivity
Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.
Smiles
O=C(C1CCCCC1)N1CC2N(CCC3=C2C=CC=C3)C(=O)C1
Molecular Formula
C19H24N2O2
Molecular Weight
312.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
B2011-5.1Praziquantel

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