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Atabecestat

CAT: 0931-T14338-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14338-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1200493-78-2
Target
BACE, Beta-Secretase
Related Pathways
Neuroscience
Purity
0.9977
Bioactivity
Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].
Smiles
C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
Molecular Formula
C18H14FN5OS
Molecular Weight
367.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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