ALLO-2

• Target:

  Hedgehog/Smoothened|||Smo

• Related Pathways:

  GPCR/G Protein|||Stem Cells

• Purity:

  0.9919

• Bioactivity:

  ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

• Smiles:

  FC(F)(F)Oc1ccc(cc1)-c1ccnc(Nc2ccc3[nH]ncc3c2)n1

• Molecular Formula:

  C18H12F3N5O

• Molecular Weight:

  371.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1357350-60-7