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Capecitabine

CAT: 0931-T1408-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0931-T1408-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
154361-50-9
Target
DNA/RNA Synthesis, Apoptosis, Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Apoptosis
Purity
>99.99%
Bioactivity
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU) ; subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.
Smiles
O[C@H]1[C@@H](O[C@H](C)[C@H]1O)N2C(=O)N=C(NC(OCCCCC)=O)C(F)=C2
Molecular Formula
C15H22FN3O6
Molecular Weight
359.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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A8647-50Capecitabine
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