A-443654

• CAS Number :

  552325-16-3

• Target :

  PKA|||PKC|||Src|||Chk|||VEGFR|||Akt|||FLT|||Casein Kinase|||ERK|||MAPK|||GSK-3|||S6 Kinase|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||Stem Cells|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Metabolism

• Purity :

  0.9951

• Bioactivity :

  A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM) .

• Smiles :

  C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5

• Molecular Formula :

  C24H23N5O

• Molecular Weight :

  397.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C