Tadalafil

• Target:

  PDE|||Apoptosis

• Related Pathways:

  Apoptosis|||Metabolism

• Purity:

  0.9953

• Bioactivity:

  Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP) -specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby causing prolonged muscle relaxation, vasodilation, and enhanced penile erection.

• Smiles:

  O=C1N2[C@@H](C3=C(C=4C(N3)=CC=CC4)C[C@@]2(C(=O)N(C)C1)[H])C=5C=C6C(=CC5)OCO6

• Molecular Formula:

  C22H19N3O4

• Molecular Weight:

  389.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  171596-29-5