Dyclonine hydrochloride

Chemical Information
Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
| CAS Number | 536-43-6 |
| PubChem CID | 68304 |
| IUPAC Name | 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one;hydrochloride |
| Molecular Formula | C18H28ClNO2 |
| Molecular Weight | 325.9 |
| Topological Polar Surface Area | 29.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 8 |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 292 |
| Property | Value |
|---|---|
| Molecular Weight | 325.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 8 |
| Exact Mass | 325.1808568 |
| Monoisotopic Mass | 325.1808568 |
| Topological Polar Surface Area | 29.5 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 292 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
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