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Homocarbonyltopsentin

CAT: 0931-T13723-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T13723-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
172286-77-0
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 μM) .
Smiles
Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
Molecular Formula
C21H14N4O3
Molecular Weight
370.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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