AP5

• Target:

  Others|||GPCR

• Related Pathways:

  GPCR/G Protein|||Others|||Endocrinology/Hormones

• Bioactivity:

  AP5 is a potent and selective agonist for the GPR40 receptor with positive allosteric modulation of endogenous ligands (AgoPAM) . AP5 demonstrates a rat hIP1 EC50 of 0.49 nM against the GPR40 receptor.

• Smiles:

  [C@@H]([C@@H](C(O)=O)C)(C=1C=C2C(=CC1)CC[C@H](O2)C3=C(F)C=C(C=C3)C=4C=C(OC)N=CC4)[C@H]5CC5

• Molecular Formula:

  C28H28FNO4

• Molecular Weight:

  461.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1623194-37-5