(R) -BAY1238097

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9877

• Bioactivity:

  (R) -BAY1238097 represents the R-isomer of BAY1238097, which exhibits relatively lower activity compared to its counterpart. BAY1238097 is a highly potent and selective inhibitor targeting the binding of BET proteins to histones, demonstrating significant anti-proliferative effects in various acute myeloid leukemia (AML) and multiple myeloma (MM) models. The high activity is achieved through the down-regulation of c-Myc levels and the subsequent modulation of its downstream transcriptome.

• Smiles:

  O(C)C=1C=C2C(=NN(C(NC)=O)[C@H](C)CC2=CC1OC)C3=CC=C(C=C3)N4CCN(C)CC4

• Molecular Formula:

  C25H33N5O3

• Molecular Weight:

  451.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1564269-85-7