WAY-213613

• Target:

  Transporter

• Related Pathways:

  Metabolism

• Bioactivity:

  WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85 nM EAAT2), displaying 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 ?M, respectively) . WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors.

• Smiles:

  N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O

• Molecular Formula:

  C16H13BrF2N2O4

• Molecular Weight:

  415.19

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  868359-05-1