Products for Research Use Only
RegisterLogin

Seviteronel

CAT: 0931-T13312L-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T13312L-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1610537-15-9
Target
Cytochromes P450, Androgen Receptor
Related Pathways
Metabolism, Endocrinology/Hormones
Purity
>99.99%
Bioactivity
Seviteronel (VT-464) is a novel CYP17 cleavage enzyme inhibitor and androgen receptor antagonist used in breast and prostate cancer research.
Smiles
CC(C)[C@@](O)(c1c[nH]nn1)c1ccc2cc(OC(F)F)c(OC(F)F)cc2c1
Molecular Formula
C18H17F4N3O3
Molecular Weight
399.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Seviteronel

Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.

CAS Number1610537-15-9
PubChem CID78357816
IUPAC Name(1S)-1-[6,7-bis(difluoromethoxy)naphthalen-2-yl]-2-methyl-1-(2H-triazol-4-yl)propan-1-ol
Molecular FormulaC18H17F4N3O3
Molecular Weight399.3
XLogP4.7
Topological Polar Surface Area80.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Heavy Atom Count28
Formal Charge0
Complexity516
SMILES
CC(C)[C@](C1=CC2=CC(=C(C=C2C=C1)OC(F)F)OC(F)F)(C3=NNN=C3)O
InChI
InChI=1S/C18H17F4N3O3/c1-9(2)18(26,15-8-23-25-24-15)12-4-3-10-6-13(27-16(19)20)14(28-17(21)22)7-11(10)5-12/h3-9,16-17,26H,1-2H3,(H,23,24,25)/t18-/m0/s1
InChIKey
ZBRAJOQFSNYJMF-SFHVURJKSA-N
Chemical Structure
2D Structure
2D structure of Seviteronel
CAS: 1610537-15-9
CID: 78357816
Formula: C18H17F4N3O3
MW: 399.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight399.3
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass399.12060406
Monoisotopic Mass399.12060406
Topological Polar Surface Area80.3 Ų
Heavy Atom Count28
Formal Charge0
Complexity516
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
KPC53715-01Seviteronel
A20996-10Seviteronel 10mg
MBS5754113Seviteronel racemate
A20996-100Seviteronel 100mg
A20996-50Seviteronel 50mg
A20996-5Seviteronel 5mg
A20996-1Seviteronel 1mg
HY-15996B-01Seviteronel (racemate)
A20996-25Seviteronel 25mg
HY-15996A-01Seviteronel (R enantiomer)

Popular Products