Artemether

Chemical Information
Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is an organic peroxide, a sesquiterpenoid, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative.
| CAS Number | 71963-77-4 |
| PubChem CID | 68911 |
| IUPAC Name | (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane |
| Molecular Formula | C16H26O5 |
| Molecular Weight | 298.37 |
| XLogP | 3.1 |
| Topological Polar Surface Area | 46.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 429 |
| Property | Value |
|---|---|
| Molecular Weight | 298.37 |
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 298.17802393 |
| Monoisotopic Mass | 298.17802393 |
| Topological Polar Surface Area | 46.2 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 429 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
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