Ouabain octahydrate

• Target:

  Autophagy|||ATPase

• Related Pathways:

  Autophagy|||Membrane transporter/Ion channel

• Purity:

  0.999

• Bioactivity:

  Ouabain octahydrate (Acocantherine) is a cardiac glycoside that inhibits Na (+) /K (+) ATPase. Ouabain octahydrate regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.

• Smiles:

  O.O.O.O.O.O.O.O.CC1OC(OC2CC(O)C3(CO)C4C(O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C2=CC(=O)OC2)C(O)C(O)C1O

• Molecular Formula:

  C29H44O12·8H2O

• Molecular Weight:

  728.77

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  11018-89-6