Toceranib

• CAS Number :

  356068-94-5

• Target :

  VEGFR|||c-Kit|||PDGFR

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9762

• Bioactivity :

  Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit (with Kis of 5 and 6 nM for PDGFR? and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.

• Smiles :

  Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCCC1

• Molecular Formula :

  C22H25FN4O2

• Molecular Weight :

  396.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C