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Toceranib

CAT: 0931-T13178-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T13178-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
356068-94-5
Target
VEGFR, c-Kit, PDGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9762
Bioactivity
Toceranib (PHA 291639E) phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit (with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.
Smiles
Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCCC1
Molecular Formula
C22H25FN4O2
Molecular Weight
396.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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