Minocycline

• Target:

  Potassium Channel|||ribosome|||Calcium Channel|||Apoptosis|||Antioxidant|||MDM-2/p53|||HIF/HIF Prolyl-Hydroxylase|||ROS|||Antibiotic|||Antibacterial

• Related Pathways:

  Immunology/Inflammation|||Microbiology/Virology|||Membrane transporter/Ion channel|||Chromatin/Epigenetic|||Oxidation-Reduction|||Metabolism|||Apoptosis

• Bioactivity:

  Minocycline is a broad-spectrum and highly lipophilic tetracycline antibiotic with the advantages of being orally administrable and able to penetrate the blood-brain barrier. It binds to the 30S ribosomal subunit to inhibit protein synthesis, is effective against both Gram-positive and Gram-negative bacteria, and also has neuroprotective, anti-inflammatory, and antioxidant effects.

• Smiles:

  O[C@]12[C@] ([C@H] (N (C) C) C (O) =C (C (N) =O) C1=O) (C[C@]3 (C (=C2O) C (=O) C=4C (C3) =C (N (C) C) C=CC4O) [H]) [H]

• Molecular Formula:

  C23H27N3O7

• Molecular Weight:

  457.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  10118-90-8