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Minocycline

CAT: 0931-T131626Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T131626Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
10118-90-8
Target
Potassium Channel, ribosome, Calcium Channel, Apoptosis, Antioxidant, MDM-2/p53, HIF/HIF Prolyl-Hydroxylase, ROS, Antibiotic, Antibacterial
Related Pathways
Immunology/Inflammation, Microbiology/Virology, Membrane transporter/Ion channel, Chromatin/Epigenetic, Oxidation-Reduction, Metabolism, Apoptosis
Bioactivity
Minocycline is a broad-spectrum and highly lipophilic tetracycline antibiotic with the advantages of being orally administrable and able to penetrate the blood-brain barrier. It binds to the 30S ribosomal subunit to inhibit protein synthesis, is effective against both Gram-positive and Gram-negative bacteria, and also has neuroprotective, anti-inflammatory, and antioxidant effects.
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O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C(C3)=C(N(C)C)C=CC4O)[H])[H]
Molecular Formula
C23H27N3O7
Molecular Weight
457.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C