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Timegadine

CAT: 0931-T13160-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T13160-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
71079-19-1
Target
COX
Related Pathways
Neuroscience, Immunology/Inflammation
Bioactivity
Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates and in washed rabbit platelets.
Smiles
N(=C(NC1=NC=CS1)NC2CCCCC2)C=3C4=C(N=C(C)C3)C=CC=C4
Molecular Formula
C20H23N5S
Molecular Weight
365.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C