Thiocillin I

• Target:

  Antibiotic|||Antibacterial

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  Thiocillin I, a thiopeptide antibiotic, demonstrates potent in vitro antibacterial effects against Gram-positive bacteria. This compound exhibits minimum inhibitory concentrations (MICs) of 2 ?g/mL, 0.5 ?g/mL, 4 ?g/mL, and 0.5 ?g/mL against S. aureus 1974149, E. faecalis 1674621, B. subtilis ATCC 6633, and S. pyogenes 1744264, respectively.

• Smiles:

  [H][C@]1(NC(=O)c2csc(n2)[C@@H](NC(=O)c2csc(n2)\C(NC(=O)[C@@]([H])(NC(=O)c2csc(n2)-c2ccc(nc2-c2csc1n2)-c1nc(cs1)-c1nc(cs1)C(=O)N\C(=C/C)C(=O)NC[C@@H](C)O)[C@@H](C)O)=C\C)C(C)(C)O)[C@@H](C)O

• Molecular Formula:

  C48H49N13O10S6

• Molecular Weight:

  1160.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  59979-01-0