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TAS4464 hydrochloride

CAT: 0931-T13090-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T13090-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1848959-11-4
Target
E1/E2/E3 Enzyme, NEDD8
Related Pathways
Ubiquitination, Metabolism
Purity
0.9896
Bioactivity
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50 of 0.955 nM) .
Smiles
Cl.CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12
Molecular Formula
C21H24ClFN6O6S
Molecular Weight
542.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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