Human IgA lambda (dimer)

Human IgA lambda (dimer)

• Background: Purified Human IgA1 lambda may be used as an IgA reference antigen, calibrator, coating protein and blocking agent in a variety of immunoassays including immunodiffusion, immunoelectrophoresis, ELISA, Western blotting, dot-immunobinding assays (DIBA), haemagglutination, and cell-binding assays.
• Type: Proteins and Peptides
• Applications: ELISA
• Field of Research: Immunology
• Concentration: 1 mg/mL
• Form: Chromatographically purified Human IgA1 lambda, dimer. 0,5 mL solution of 1 mg/mL P 444; No preservative added_x000D_ This IgA1 consists mainly of dimers (as shown in; Non-reducing PAGE) and may contain traces of J chain._x000D_ Confirmed by immunoelectrophoresis and double radial immunodiffusion (Ouchterlony); Not less than 98% as determined by agar-gel electrophoresis.
• Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• References & Citations: Hansen IS, Hoepel W, Zaat SAJ, Baeten DLP, den Dunnen J. Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through FcαRI-TLR Cross-Talk. J Immunol. 2017;199(12):4124-4131. doi:10.4049/jimmunol.1700883
• Shipping Conditions: Ambient Temperature
• Storage Conditions: After arrival store at +4°C; Prolonged storage may be at -20°C Allow to stand at ambient temperature for 5-10 minutes to reach equilibrium; Working dilutions may be prepared by adding the required amount of phosphate buffered saline (PBS), should not be refrozen and preferably used within 24 hours; Repeated thawing and freezing should be avoided; If a slight precipitation occurs upon storage, this should be removed by centrifugation and will not affect the performance of the product