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MLR12

CAT: 0804-HY-P5521-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P5521-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MLR12 is a Trem1 inhibitory peptide. mLR12 decreases aortic rupture rate in BAPN-induced Thoracic aortic aneurysm and dissection (TAAD) mice model[1].
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mlr12.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(NCC(N[C@@H](CS)C(N[C@@H](C(C)C)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C55H84N14O23S
Molecular Weight
1341.40
References & Citations
[1]Liu X, et al. Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection. Cell Discov. 2022 Feb 8;8 (1) :11.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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