Products for Research Use Only

Ochratoxin B

CAT: 0804-HY-N6786Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N6786Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ochratoxin B is an orally active secondary metabolite of Aspergillus ochraceus and non-chlorinated analog of the mycotoxin Ochratoxin A. Ochratoxin B reduces the toxic effects of Ochratoxin A. Ochratoxin B inhibits cell division. Ochratoxin B causes craniofacial malformations in Xenopus laevis embryos[1][2][3][4][5][6].
CAS Number
4825-86-9
UNSPSC
12352005
Hazard Statement
H225, H302+H312+H332, H319
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ochratoxin-b.html
Purity
99.90
Solubility
DMSO : 15 mg/mL (ultrasonic; warming)
Smiles
O=C1O[C@H](CC2=C1C(O)=C(C=C2)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)C
Molecular Formula
C20H19NO6
Molecular Weight
369.37
Precautions
H225, H302+H312+H332, H319
References & Citations
[1]Knasmüller S, et al. Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment. Nutr Cancer. 2004;50 (2) :190-7. |[2]O'Brien E, et al. Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system. Birth Defects Res B Dev Reprod Toxicol. 2005 Oct;74 (5) :417-23.|[3]Dietrich DR, et al. Species- and sex-specific renal cytotoxicity of ochratoxin A and B in vitro. Exp Toxicol Pathol. 2001 Jun;53 (2-3) :215-25. |[4]Csenki Z, et al. The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food Chem Toxicol. 2021 Dec;158:112674.|[5]Mally A, et al. Biotransformation and nephrotoxicity of ochratoxin B in rats. Toxicol Appl Pharmacol. 2005 Aug 1;206 (1) :43-53.|[6]Størmer FC, et al. Metabolism of ochratoxin B and its possible effects upon the metabolism and toxicity of ochratoxin A in rats. Appl Environ Microbiol. 1985 May;49 (5) :1108-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite