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Siguazodan

CAT: 0931-T12913-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T12913-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
115344-47-3
Target
PDE
Related Pathways
Metabolism
Purity
0.9987
Bioactivity
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III) ) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.
Smiles
CN\C(NC#N)=N/c1ccc(cc1)C1=NNC(=O)CC1C
Molecular Formula
C14H16N6O
Molecular Weight
284.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C