Oxiconazole nitrate

• Target:

  Cytochromes P450|||Antifection|||Antifungal|||Antibiotic

• Related Pathways:

  Microbiology/Virology|||Metabolism

• Purity:

  0.9973

• Bioactivity:

  Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This disruption of membrane synthesis and integrity alters permeability, promotes loss of essential intracellular components, and inhibits fungal cell growth.

• Smiles:

  [N+](=O)([O-])O.C(=N\OCc1c(cc(cc1)Cl)Cl)(/c1c(cc(cc1)Cl)Cl)\Cn1ccnc1

• Molecular Formula:

  C18H13Cl4N3O·HNO3

• Molecular Weight:

  492.14

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  64211-46-7