GRPP (human)

• Description :

  GRPP (human) is a 30 amino acid Gcg-derived peptide. GRPP (human) causes slight increases in plasma insulin and decreases in plasma glucagon. GRPP (human) does not affect insulin secretion in rat islets[1].

• UNSPSC :

  12352209

• Target :

  GCGR

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/grpp-human.html

• Purity :

  98.94

• Solubility :

  10 mM in DMSO

• Smiles :

  C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CCC(O)=O)=O)CC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CC(O)=O)(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCCNC(=N)N)=O)CO)=O)=O)CO)=O)C)=O)CO)=O)CCC(N)=O)=O)C)=O)CC(O)=O)=O)CCC2)CC(C)C)=O)CO)=O)CC(O)=O)=O)CCC1

• Molecular Formula :

  C136H215N41O58S

• Molecular Weight :

  3384.47

• References & Citations :

  [1]Lynda Whiting, et al. Glicentin-related pancreatic polypeptide inhibits glucose-stimulated insulin secretion from the isolated pancreas of adult male rats. Physiol Rep. 2015 Dec;3 (12) :e12638.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [1132745-52-8]