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PT2399

CAT: 0931-T12675L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T12675L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1672662-14-4
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Angiogenesis, Metabolism, Chromatin/Epigenetic
Purity
0.9945
Bioactivity
PT2399 is a first-in-class, orally available, small molecule inhibitor of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β. PT2399 displays potent antitumor activity in vivo
Smiles
O[C@H]1c2c(CC1(F)F)c(Oc1cc(F)cc(c1)C#N)ccc2S(=O)(=O)C(F)F
Molecular Formula
C17H10F5NO4S
Molecular Weight
419.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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