PF-06250112

• CAS Number :

  1609465-89-5

• Target :

  BTK

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity :

  PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively) .

• Smiles :

  C(N)(=O)C=1C(=NN(C1N)[C@@H]2CN(C#N)CCC2)C3=CC=C(OC4=C(F)C=C(F)C=C4)C=C3

• Molecular Formula :

  C22H20F2N6O2

• Molecular Weight :

  438.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C