Peruvoside

• Target :

  Apoptosis|||Autophagy|||STAT|||JNK|||EGFR|||ATPase|||PI3K|||Src|||Wnt/beta-catenin

• Related Pathways :

  Cytoskeletal Signaling|||Membrane transporter/Ion channel|||MAPK|||Stem Cells|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||Apoptosis|||Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis

• Bioactivity :

  Peruvoside (Encordin) is a natural cardiac glycoside that inhibits Na+/K+-ATPase to increase myocardial contractility; causes cell cycle arrest in leukemia stem cells at the G?/M phase, and; inhibits NSCLC cell growth as a Src inhibitor; and induces apoptosis in cancer cells through MAPK Wnt / ?-catenin and PI3K / AKT / mTOR .

• Smiles :

  C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@@]1(C[C@@H](O[C@H]6[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O6)CC2)[H])[H])[H]

• Molecular Formula :

  C30H44O9

• Molecular Weight :

  548.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1182-87-2