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Deferoxamine

CAT: 0931-T124358-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T124358-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
70-51-9
Target
Antioxidant, Apoptosis, Reactive Oxygen Species, Akt, HIF/HIF Prolyl-Hydroxylase, Autophagy, ROS, HIF
Related Pathways
NF-κB, Autophagy, Oxidation-Reduction, Immunology/Inflammation, PI3K/Akt/mTOR signaling, Angiogenesis, Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism, Apoptosis
Purity
0.9997
Bioactivity
Deferoxamine (Desferrioxamine B) is an iron chelator. Deferoxamine can be used to reduce the accumulation and deposition of iron in tissues. Deferoxamine can improve neurological dysfunction by inhibiting ferroptosis and neuroinflammation after traumatic brain injury. It has antioxidant, anti-proliferation and anti-tumor activities, and can induce the production of HIF-1α, apoptosis and autophagy in cancer cells. It can be used to treat acute iron toxicity and COVID-19 related diseases.
Smiles
O=C(NCCCCCN(O)C(=O)C)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
Molecular Formula
C25H48N6O8
Molecular Weight
560.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C