Alvimopan

• Target :

  Opioid Receptor

• Related Pathways :

  GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones

• Purity :

  0.9997

• Bioactivity :

  Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4- (3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, this agent binds to mu-opioid receptors in the gut, thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.

• Smiles :

  C[C@H]1CN(C[C@H](Cc2ccccc2)C(=O)NCC(O)=O)CC[C@@]1(C)c1cccc(O)c1

• Molecular Formula :

  C25H32N2O4

• Molecular Weight :

  424.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  156053-89-3