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N-Desmethyltamoxifen

CAT: 0931-T12148L-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T12148L-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
31750-48-8
Target
Estrogen Receptor/ERR, Others, Endogenous Metabolite, PKC, Drug Metabolite
Related Pathways
Cytoskeletal Signaling, Endocrinology/Hormones, Chromatin/Epigenetic, Metabolism, Others
Bioactivity
N-Desmethyltamoxifen, the principal metabolite of tamoxifen in humans, serves as an efficacious modulator of ceramide metabolism within human AML cells by inhibiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Although it demonstrates weak antiestrogenic properties, it acts as a protein kinase C (PKC) inhibitor with a potency ten times greater than that of tamoxifen.
Smiles
C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCNC)C=C2)/C3=CC=CC=C3
Molecular Formula
C25H27NO
Molecular Weight
357.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
GTR19229699-01N-Desmethyltamoxifen
MBS5753541N-Desmethyltamoxifen hydrochloride
HY-129099A-01N-Desmethyltamoxifen (hydrochloride)
HY-129099AR-01N-Desmethyltamoxifen (hydrochloride) (Standard)
D3220-90NN-Desmethyltamoxifen Methanethiosulfonate Hydrobromide
CS-P-09209N-DesmethylTamoxifen (E/Z mixture)
CS-O-55644(E) -N-desmethyltamoxifen-4-O-glucuronide
MBS6044133-01N-Desmethyltamoxifen-ethyl-d5 (N-Demethyltamoxifen-ethyl-d5)
D3220-90MN-Desmethyltamoxifen, Hydrochloride (N-Demethyltamoxifen, Hydrochloride_x000B_ (Z) -2-[4- (1,2-Diphenyl-1-butenyl) phenoxy]-N-methyl-ethanamine)
MBS6090073-01N-Desmethyltamoxifen, Hydrochloride (N-Demethyltamoxifen, Hydrochloride(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methyl-ethanamine)

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