Products for Research Use Only
RegisterLogin

LY3020371 hydrochloride

CAT: 0931-T11911-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T11911-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1377615-44-5
Target
GluR
Related Pathways
Neuroscience
Bioactivity
LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM.
Smiles
Cl.[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)([C@H](CSc1ccc(F)c(F)c1)[C@H]2O)C(O)=O
Molecular Formula
C15H16ClF2NO5S
Molecular Weight
395.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

LY3020371 (hydrochloride)
CAS Number1377615-44-5
PubChem CID69669746
IUPAC Name(1S,2R,3S,4S,5R,6R)-2-amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxybicyclo[3.1.0]hexane-2,6-dicarboxylic acid;hydrochloride
Molecular FormulaC15H16ClF2NO5S
Molecular Weight395.8
Topological Polar Surface Area146
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count25
Formal Charge0
Complexity552
SMILES
C1=CC(=C(C=C1SC[C@@H]2[C@H]([C@H]3[C@@H]([C@H]3[C@@]2(C(=O)O)N)C(=O)O)O)F)F.Cl
InChI
InChI=1S/C15H15F2NO5S.ClH/c16-7-2-1-5(3-8(7)17)24-4-6-12(19)9-10(13(20)21)11(9)15(6,18)14(22)23;/h1-3,6,9-12,19H,4,18H2,(H,20,21)(H,22,23);1H/t6-,9+,10+,11+,12-,15+;/m1./s1
InChIKey
XETSGLSGWGGOTN-JPWNOPPSSA-N
Chemical Structure
2D Structure
2D structure of LY3020371 (hydrochloride)
CAS: 1377615-44-5
CID: 69669746
Formula: C15H16ClF2NO5S
MW: 395.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight395.8
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass395.0405778
Monoisotopic Mass395.0405778
Topological Polar Surface Area146 Ų
Heavy Atom Count25
Formal Charge0
Complexity552
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
T38791LY3020371
T77217Saccharopine hydrochloride
T23379-01Solifenacin hydrochloride
T38447-01BN82002 hydrochloride
T40896Bromchlorbuterol hydrochloride
T33939-01Dagrocorat hydrochloride
T36365-01KAPA hydrochloride
T0204Protriptyline hydrochloride
T12877-01Seltorexant hydrochloride
T24181-01Isothipendyl hydrochloride

Alternative Products

CatalogName
MBS3843609-01LY3020371 hydrochloride
HY-123820-01LY3020371 (hydrochloride)
A19152-50LY3020371 hydrochloride 50mg
A19152-1LY3020371 hydrochloride 1mg
A19152-10LY3020371 hydrochloride 10mg
A19152-5LY3020371 hydrochloride 5mg
A19152-100LY3020371 hydrochloride 100mg
GTR19189700LY3020371
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)

Popular Products