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Bifonazole

CAT: 0931-T1187-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0931-T1187-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
60628-96-8
Target
Cytochromes P450, Antifungal, Antibiotic
Related Pathways
Metabolism, Microbiology/Virology
Purity
>99.99%
Bioactivity
Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase) . It works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. This is vital in the cell membrane structure of the fungus. Its inhibition leads to cell lysis. The disruption in production of ergosterol disrupts the cell membrane and causes holes to appear. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out.
Smiles
C(C1=CC=C(C=C1)C2=CC=CC=C2)(N3C=CN=C3)C4=CC=CC=C4
Molecular Formula
C22H18N2
Molecular Weight
310.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C