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LCH-7749944

CAT: 0931-T11826-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11826-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
796888-12-5
Target
PAK, Apoptosis
Related Pathways
Apoptosis, Cytoskeletal Signaling
Purity
0.9948
Bioactivity
LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 μM, effectively suppressing the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 pathway and inducing apoptosis.
Smiles
COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1
Molecular Formula
C20H22N4O2
Molecular Weight
350.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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