Temozolomide

• Target :

  DNA Alkylator/Crosslinker|||Apoptosis|||Autophagy|||DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/Checkpoint|||Autophagy|||Apoptosis|||DNA Damage/DNA Repair

• Purity :

  0.9987

• Bioactivity :

  Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.

• Smiles :

  CN1N=NC2=C(N=CN2C1=O)C(N)=O

• Molecular Formula :

  C6H6N6O2

• Molecular Weight :

  194.15

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  85622-93-1