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K145

CAT: 0931-T11739-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T11739-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1309444-75-4
Target
Others, Apoptosis, S1P Receptor
Related Pathways
Others, Apoptosis, GPCR/G Protein
Bioactivity
K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM.
Smiles
C(CN)N1C(=O)C(=CCCC2=CC=C(OCCCC)C=C2)SC1=O
Molecular Formula
C18H24N2O3S
Molecular Weight
348.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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