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HL271

CAT: 0931-T11570-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T11570-03Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1422365-52-3
Target
AMPK, OXPHOS
Related Pathways
PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Apoptosis
Bioactivity
HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.
Smiles
Cl.FC(F)(F)OC1=CC=C(C=C1)NC(=N)NC(=N)N2CCCC2
Molecular Formula
C13H17ClF3N5O
Molecular Weight
351.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Lixumistat hydrochloride
CAS Number1422365-52-3
PubChem CID146047146
IUPAC NameN'-[N'-[4-(trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboximidamide;hydrochloride
Molecular FormulaC13H17ClF3N5O
Molecular Weight351.75
Topological Polar Surface Area89.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity424
SMILES
C1CCN(C1)/C(=N/C(=NC2=CC=C(C=C2)OC(F)(F)F)N)/N.Cl
InChI
InChI=1S/C13H16F3N5O.ClH/c14-13(15,16)22-10-5-3-9(4-6-10)19-11(17)20-12(18)21-7-1-2-8-21;/h3-6H,1-2,7-8H2,(H4,17,18,19,20);1H
InChIKey
FSEAYPJRYNBFTN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Lixumistat hydrochloride
CAS: 1422365-52-3
CID: 146047146
Formula: C13H17ClF3N5O
MW: 351.75
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight351.75
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass351.1073724
Monoisotopic Mass351.1073724
Topological Polar Surface Area89.2 Ų
Heavy Atom Count23
Formal Charge0
Complexity424
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19205643-01HL271

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