GZD856

• Target:

  Apoptosis|||PDGFR|||Bcr-Abl

• Related Pathways:

  Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Cytoskeletal Signaling

• Bioactivity:

  GZD856 is an orally bioavailable PDGFR?/? inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.

• Smiles:

  C(C1=C(C(F)(F)F)C=C(NC(=O)C2=CC(C#CC3=CN4C(N=C3)=CC=N4)=C(C)C=C2)C=C1)N5CCN(C)CC5

• Molecular Formula:

  C29H27F3N6O

• Molecular Weight:

  532.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1257628-64-0