GW274150

• CAS Number :

  210354-22-6

• Target :

  NOS|||NO Synthase

• Related Pathways :

  Immunology/Inflammation

• Purity :

  >99.99%

• Bioactivity :

  GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS) .GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.

• Smiles :

  C([C@@H](C(O)=O)N)CSCCNC(C)=N

• Molecular Formula :

  C8H17N3O2S

• Molecular Weight :

  219.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C