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IPN60090

CAT: 0931-T11412-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11412-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1853164-83-6
Target
Glutaminase, transporter
Related Pathways
Proteases/Proteasome, Metabolism
Purity
>99.99%
Bioactivity
IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1) -specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, selectively targets, binds, and inhibits human glutaminase, and can be used to study GLS1-mediated diseases.
Smiles
CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1
Molecular Formula
C24H27F3N8O3
Molecular Weight
532.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C