GLP-26

• Target :

  HBV

• Related Pathways :

  Microbiology/Virology

• Purity :

  0.9862

• Bioactivity :

  GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 ?M. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.

• Smiles :

  Cc1c(C(=O)C(=O)NCC#C)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1

• Molecular Formula :

  C19H17F2N3O3

• Molecular Weight :

  373.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2133017-36-2