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GLP-26

CAT: 0931-T11409-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11409-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2133017-36-2
Target
HBV
Related Pathways
Microbiology/Virology
Purity
0.9862
Bioactivity
GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.
Smiles
Cc1c(C(=O)C(=O)NCC#C)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1
Molecular Formula
C19H17F2N3O3
Molecular Weight
373.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C