FMF-04-159-2

• Target :

  Others|||CDK|||Wnt/beta-catenin

• Related Pathways :

  Cell Cycle/Checkpoint|||Stem Cells|||Others|||Cytoskeletal Signaling

• Purity :

  0.9657

• Bioactivity :

  FMF-04-159-2 is a potent covalent cell cycle protein-dependent kinase 14 (CDK14) inhibitor with IC?? of 39.6 nM for CDK14 and 256 nM for CDK2.FMF-04-159-2 is able to reduce ?-synuclein (?-Syn) aggregation in neurons and plays a role in Parkinson's disease models, and also inhibits triple-negative breast cancer (TNBC) progression and metastasis by attenuating Wnt/?-catenin signaling.

• Smiles :

  N(C(=O)C1=C(Cl)C=C(Cl)C=C1Cl)C=2C(C(NC3CCN(S(=O)(=O)C4=CC(NC(/C=C/CN(C)C)=O)=CC=C4)CC3)=O)=NNC2

• Molecular Formula :

  C28H30Cl3N7O5S

• Molecular Weight :

  683.01

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2364489-81-4