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Fluorobexarotene

CAT: 0931-T11303-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T11303-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1190848-23-7
Target
Retinoid Receptor
Related Pathways
Metabolism
Purity
0.9923
Bioactivity
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
Smiles
CC1=CC2=C(C=C1C(=C)C1=CC(F)=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C
Molecular Formula
C24H27FO2
Molecular Weight
366.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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