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Gramicidin

CAT: 0931-T1130-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T1130-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1405-97-6
Target
MRP, Antibiotic, Antibacterial
Related Pathways
Immunology/Inflammation, Microbiology/Virology
Purity
0.9703
Bioactivity
Gramicidin (Gramicidine) is an antimicrobial peptide. Gramicidin dimers form ion channel-like pores in the cell membranes and organelles of bacterial and animal cells, allowing inorganic monovalent ions, such as potassium and sodium ions, to pass freely through the pores by diffusion, disrupting the important ionic gradient between membranes and thus killing the cells by various actions. Gramicidin is effective against Gram-positive bacteria such as Bacillus subtilis and Staphylococcus aureus, but is not as effective against Gram-negative bacteria such as Escherichia coli.
Smiles
C[C@@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC7=CNC8=CC=CC=C87)C(=O)NCCO)NC(=O)CNC(=O)[C@H](C(C)C)NC=O
Molecular Formula
C99H140N20O17
Molecular Weight
1882.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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