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(+) -Shikonin

CAT: 0931-T1125-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T1125-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
517-89-5
Target
PKM, HIV Protease, NF-κB, Chloride channel, AIM2, TNF
Related Pathways
Apoptosis, Metabolism, Membrane transporter/Ion channel, Immunology/Inflammation, NF-κB, Proteases/Proteasome, Microbiology/Virology
Purity
0.999
Bioactivity
(+) -Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. (+) - Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
Smiles
CC(C)=CC[C@@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
Molecular Formula
C16H16O5
Molecular Weight
288.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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