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EML741

CAT: 0931-T11185Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T11185Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2328074-38-8
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
EML741 also inhibits DNMT1 (IC50, 3.1 μM), with no effect on DNMT3a or DNMT3b. EML741 exhibits low cell toxicity, and is membrane permeable and blood-brain barrier penetrated. EML741 is a histone lysine methyltransferase G9a/GLP inhibitor, with an IC50 of 23 nM, Kd of 1.13 μM for G9a.
Smiles
N(C=1C=2C(N=C(CN1)C3CCCCC3)=CC(OCCCN4CCCC4)=C(OC)C2)C5CCN(C(C)C)CC5
Molecular Formula
C31H49N5O2
Molecular Weight
523.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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