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DUPA (OtBu) -OH

CAT: 0931-T11122-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T11122-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1026987-94-9
Target
PSMA
Related Pathways
Immunology/Inflammation
Purity
0.9974
Bioactivity
DUPA (OtBu) -OH is a precursor of DUPA, which is used as a targeting moiety to actively deliver Docetaxel (DTX) for treating Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer, with PSMA showing high affinity for DUPA (Ki = 8 nM) .
Smiles
CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C
Molecular Formula
C23H40N2O9
Molecular Weight
488.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C