VX-984

• Target :

  DNA-PK

• Related Pathways :

  PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

• Purity :

  0.9998

• Bioactivity :

  VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.

• Smiles :

  [2H]c1nc(C)nc([2H])c1-c1cc(NC[C@@H](C)c2cccc3c(ccnc23)C(=O)NC)ncn1

• Molecular Formula :

  C23H21D2N7O

• Molecular Weight :

  415.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1476074-39-1