VX-984

CAT: 0931-MF-0018085-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0018085-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1476074-39-1
Target
DNA-PK
Related Pathways
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair
Purity
0.9998
Bioactivity
VX-984 (M9831) is an oral, selective DNA-PK inhibitor that can cross the blood-brain barrier. VX-984 inhibited the conjugation of non-homologous terminal NHEJ and acted on DSBs to break DNA double strand. VX-984 is commonly seen in glioblastoma (GBM) and non-small cell lung cancer (NSC-LC) studies.
Smiles
[2H]c1nc(C)nc([2H])c1-c1cc(NC[C@@H](C)c2cccc3c(ccnc23)C(=O)NC)ncn1
Molecular Formula
C23H21D2N7O
Molecular Weight
415.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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