DM3

• Target :

  Microtubule Associated|||ADC Cytotoxin

• Related Pathways :

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

• Bioactivity :

  DM3 (Maytansinoid DM3) is a maytansine mimic with disulfide or thiol groups, acting as a tubulin inhibitor and serving as the cytotoxic component in antibody-drug conjugates (ADCs) .

• Smiles :

  [H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@]([H])(OC(=O)[C@H](C)N(C)C(=O)CCC(C)S)[C@]1(C)O[C@H]1[C@@H]2C

• Molecular Formula :

  C37H52ClN3O10S

• Molecular Weight :

  766.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  796073-54-6